In the context of cholesterols function, what role do statins play?

Statins are a class of medications that primarily function by inhibiting the enzyme HMG-CoA reductase, which plays a key role in the biosynthesis of cholesterol in the liver. By doing so, statins effectively lower the production of cholesterol within the body. This decrease in cholesterol synthesis prompts the liver to pull more cholesterol from the bloodstream to meet its needs, resulting in a reduction of overall cholesterol levels in the blood.

The action of statins is particularly beneficial for individuals at risk of cardiovascular diseases, as lower cholesterol levels can lead to a decreased risk of plaque formation in the arteries, thereby reducing the likelihood of heart attacks and strokes. Statins can also have additional beneficial effects, including improving endothelial function and stabilizing atherosclerotic plaques, further contributing to cardiovascular health.