What is referred to as a change in the sequence of bases of a particular gene?

A change in the sequence of bases of a particular gene is specifically referred to as a gene mutation. Mutations can occur due to various factors, including errors during DNA replication, environmental influences, or exposure to radiation and chemicals. These alterations in the nucleotide sequence can have a range of effects on the resulting protein, from having no impact at all to causing significant changes that can lead to diseases or altered traits.

Gene expression refers to the process through which the information encoded in a gene is used to produce a functional product, typically a protein, and does not necessarily indicate a change in the sequence of the bases themselves. Genetic profiling encompasses techniques used to analyze and compare genetic information but does not involve changes to the sequence of bases in a gene. The term genome refers to the complete set of genetic material within an organism but does not specifically denote changes in individual genes.