What occurs when cancerous cells detach from the primary tumor and spread to other parts of the body?

The phenomenon that occurs when cancerous cells detach from the primary tumor and spread to other parts of the body is referred to as metastasis. During this process, the cancer cells can enter the bloodstream or lymphatic system, allowing them to travel and form new tumors in other organs or tissues, which are identified as secondary tumors.

Understanding metastasis is crucial in the study of cancer, as it often signifies a more advanced stage of the disease and can complicate treatment strategies. In contrast, apoptosis refers to programmed cell death, which is a normal process that eliminates damaged or unnecessary cells; angiogenesis refers to the formation of new blood vessels that tumors may induce to supply them with nutrients; while secondary tumors are the result of metastasis, not the mechanism itself.