What process involves the movement of particles from a region of lower concentration to one of higher concentration using ATP?

Active transport is the process that involves the movement of particles from a region of lower concentration to one of higher concentration, and this movement requires energy in the form of ATP. Active transport is essential for maintaining cell homeostasis and allows cells to accumulate necessary substances, such as ions or nutrients, against their concentration gradient.

In contrast, passive transport, facilitated diffusion, and simple diffusion do not require ATP. Passive transport involves the movement of substances along their concentration gradient, while facilitated diffusion utilizes specific transport proteins but still moves substances from high to low concentration. Simple diffusion refers to the movement of small, nonpolar molecules directly across the lipid bilayer of the cell membrane, also following their concentration gradient. Because active transport goes against this gradient and consumes energy, it is the correct answer for the described process.